Adventitious Agent NGS Investigation
Taxonomic specificity, coverage, contigs, negative controls and evidence summary.
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Adventitious Agent NGS Investigation
Bioinformatics analysis of NGS data to search for, characterise and document unexpected microbial or viral signals in R&D or investigation settings.
Possible inputs
- Single-end or paired-end FASTQ
- Processed reads or contigs when upstream analysis already exists
- Sample and sequencing-run metadata
- Negative, blank and process controls when available
- Host reference or other expected sequences to subtract when appropriate
Bioinformatics analysis
- Quality control and removal of expected / host sequences
- Taxonomic classification and specificity review
- Reference alignment, depth and breadth of coverage
- Assembly and contig analysis when supported by the data
- Comparison with negative controls and background signal
- Candidate prioritisation for review and confirmation
Results provided
- Candidate table with supporting evidence
- Genome-coverage view for retained signals
- Sample / control comparison
- Candidate contigs or sequences according to scope
- Methods, references, software versions and interactive report
Service positioning
This service is designed for discovery and bioinformatics investigation in R&D.
Interactive example